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Car signaling

「Car signaling」文章包含有:「CARandTCRformindividualsignalingsynapsesanddo...」、「CARSignalingNetworksInteractivePathway」、「Chimericantigenreceptorsignaling」、「RecentadvancesonCAR」、「RewiredsignalingnetworkinTcellsexpressingthe...」、「SignalingfromTcellreceptors(TCRs)andchimeric...」、「Tuningchargedensityofchimericantigenreceptor...」

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T cell Signalingt-cell receptor rearrangementT cell activationt cell receptor中文t-cell activation pathwaytcr-t cell therapy
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CAR and TCR form individual signaling synapses and do ...
CAR and TCR form individual signaling synapses and do ...

https://www.frontiersin.org

Chimeric antigen receptors (CARs) can be remarkably powerful in redirecting a T cell response towards defined target cells (1) while utilizing the TCR/CD3 ...

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CAR Signaling Networks Interactive Pathway
CAR Signaling Networks Interactive Pathway

https://www.cellsignal.com

CARs are synthetic proteins with a modular design intended to engage the endogenous cell signaling cascades that elicit effector T-cell functions—including ...

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Chimeric antigen receptor signaling
Chimeric antigen receptor signaling

https://www.ncbi.nlm.nih.gov

CARs, unlike the TCRs they mimic, consist of molecules in which tumor antigen recognition and intracellular activation are combined. Their ...

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Recent advances on CAR
Recent advances on CAR

https://www.frontiersin.org

This review highlights ongoing research aimed at elucidating the role of CAR domains and T-cell signaling molecules involved in these processes.

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Rewired signaling network in T cells expressing the ...
Rewired signaling network in T cells expressing the ...

https://www.embopress.org

The chimeric antigen receptor (CAR) triggers a rewired signaling pathway to activate T cells as compared to the T cell receptor (TCR).

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Signaling from T cell receptors (TCRs) and chimeric ...
Signaling from T cell receptors (TCRs) and chimeric ...

https://www.ncbi.nlm.nih.gov

TCR and CAR signaling plays a critical role in determining the T cell state, including exhaustion and memory.

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Tuning charge density of chimeric antigen receptor ...
Tuning charge density of chimeric antigen receptor ...

https://www.nature.com

Our findings suggest that the rational tuning of PCPs to optimize tonic signaling and in vivo fitness of CAR-T cells is a promising design strategy for the ...